Polyperfluoroethoxymethoxy Difluoroethyl PEG Diisostearate

AKA: Fluorinated PEG Ester, Perfluorinated Emollient

Plant-Derived

Skin Conditioner

Not Clean

Diester of isostearic acid and polyperfluoroethoxymethoxy difluoroethyl PEG ether

CAS #

162492-15-1, 88645-29-8

Form

Liquid

Functions

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Locks in moisture

Traditional Use

A highly specialized synthetic polymer developed in the late 20th century. Created to provide enhanced spreadability and conditioning in premium cosmetics with minimal residue.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

medical-approval

all-shades-safe

Potential Sensitizer

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed2 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR