murphyPolyquaternium-10
molecular structure · PubChem
AKA: Polymer JR, Polymer JR-400
Synthetic
Occlusive
Clean
OriginSynthesized from cellulose or other polysaccharide polymers modified with quaternary ammonium groups. Produced through chemical quaternization of cellulose derivatives using ammonium-containing reagents.
Cellulose, 2-(2-hydroxy-3-(trimethylammonium)propoxy)ethyl ether, chloride;Cellulose, 2-hydroxyethyl 2-[2-hydroxy-3-(trimethylammonio)propoxy]ethyl 2-hydroxy-3-(trimethylammonio)propyl ether, chloride Cellulose, ether with alpha-[2-hydroxy-3-(trimethylammonio)propyl]-omega-hydroxypoly(oxy-1,2-ethanediyl), chloride
CAS #
81859-24-7, 53568-66-4, 54351-50-7, 55353-19-0, 68610-92-4, 81859-24-7
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Reduces Static
Creates Protective Barrier
Reduces Inflammation
Locks In Moisture
Fights Bacteria
Creates protective layer
Reduces flyaways
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Product formulation test found no phototoxicity in the CIR safety assessment (CIR 156)
Mixed Eye Irritation Results
3 studies / 1 mixed / 2 not irritating (CIR 156)
Mixed Skin Irritation Results
9 studies / 1 irritating / 1 mixed / 7 not irritating / reactions minimal (CIR 156)
Mixed Sensitization Results
5 studies / 1 mixed / 4 not sensitizing (CIR 156)
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR