Polyquaternium-22

Synthetic
Occlusive
Clean
2-Propenaminium, N,N-dimethyl-N-(2-propenyl)-, chloride, polymer with 2-propenoic acid
CAS #
53694-17-0
Form
Powder
Functions
Antistatic
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Reduces Static
Creates Protective Barrier
Locks In Moisture
Reduces Inflammation
Fights Bacteria
Creates protective layer
Reduces flyaways
Traditional Use
A synthetic cationic polymer developed for the cosmetics industry in the 1980s-1990s. Engineered to provide superior conditioning and moisturizing properties in haircare formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR