murphyPolyquaternium-28
molecular structure · PubChem
Synthetic
Occlusive
Clean
OriginDerived from acrylamide and dimethylamine compounds, members of the quaternary ammonium polymer family. Synthesized through polymerization of acrylamide monomers followed by quaternization with dimethylamine.
1-Propanaminium, N, N, N-trimethyl-3-((2-methyl-1-oxo-2-propenyl)amino)-, chloride, polymer with 1-ethenyl-2-pyrrolidinone
CAS #
131954-48-8
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Reduces Static
Creates Protective Barrier
Locks In Moisture
Creates protective layer
Reduces flyaways
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Human test found no phototoxicity in the CIR safety assessment (CIR 572)
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 572)
Not a Skin Irritant
1 study / 1 not irritating (CIR 572)
Eye Irritant in Testing
1 study / 1 irritating / reactions minimal (CIR 572)
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR