Polyquaternium-33

Synthetic

Occlusive

Not Clean

Ethanaminium, N,N,N-trimethyl-2-(1-oxo-2-propenyl)oxy-, chloride, polymer with 2-propenamide

CAS #

69418-26-4

Form

Powder

Functions

Antistatic

Film Forming

Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.

Reduces Static

Creates Protective Barrier

Creates protective layer

Reduces flyaways

Traditional Use

A synthetic polymer developed in the 1990s for cosmetic formulations. Engineered to provide conditioning and styling benefits with enhanced compatibility in complex cosmetic systems.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not a Sensitizer

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

EU✔ permitted

JAPAN✔ permitted

CANADA✔ permitted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed2 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR