murphyPolyquaternium-39
molecular structure · PubChem
Synthetic
Occlusive
Not Clean
OriginDerived from acrylamide and dimethylamine, both petroleum-based synthetic chemicals. Synthesized through quaternization of polyacrylamide polymer chains with dimethyl sulfate.
2-Propenamide, polymer with N, N-dimethyl-N-2-propenyl-2-propen-1-aminium chloride and 2-propenoic acid
CAS #
25136-75-8
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Reduces Static
Creates Protective Barrier
Locks In Moisture
Reduces Inflammation
Fights Bacteria
Creates protective layer
Reduces flyaways
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 598)
Not a Skin Irritant
2 studies / 2 not irritating (CIR 598)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 598)
Concentration Guide
Leave-on0.01–3%
Rinse-off0.1–3%
0%50%100%
CIR reported use · 2011 survey
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR