murphyPolyquaternium-47
molecular structure · PubChem
AKA: 197969-51-0, Methyl prop-2-enoate;prop-2-enoic acid;trimethyl-[3-(2-methylprop-2-enoylamino)propyl]azanium;chloride
Synthetic
Occlusive
Skin Conditioner
Clean
OriginPolyquaternium-47 is a synthetic quaternary ammonium polymer derived from acrylamide or similar monomers. It is synthesized through free-radical polymerization and subsequent quaternization of polymer backbone chains.
1-Propanaminium, N,N,N-trimethyl-3-[(2-methyl-1-oxo-2-propenyl)amino]-, chloride, polymer with methyl 2-propenoate and 2-propenoic acid
Formula
C17H31ClN2O5
Mol. Weight
378.90
CAS #
197969-51-0
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Hair Fixing
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 572)
Skin Irritant in Testing
2 studies / 2 irritating / reactions slight to severe (CIR 572)
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 572)
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR