Polyquaternium-48

Synthetic

Occlusive

Not Clean

OriginSynthesized from acrylic monomers including methacryloyl ethyl betaine, 2-hydroxyethyl methacrylate, and methacryloyl ethyl trimethyl ammonium chloride. Produced through free radical polymerization of these monomers to form a quaternary ammonium polymer.

Polyquaternium-48 is the polymeric quaternary ammonium salt of formed from methacryloyl ethyl betaine, 2-hydroxyethyl methacrylate and methacryloyl ethyl trimethyl ammonium chloride

CAS #

-

Form

Powder

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

Functions

Antistatic

Film Forming

Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.

Hair Fixing

Reduces Static

Creates Protective Barrier

Creates protective layer

Reduces flyaways

Holds hair in place

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

EWG

CIR

Safe as used

Pregnancy

Yes

Concentration Guide

CIR lists it as not reported to be in use.

CIR · report published 2012

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Verified Jun 2026

Data: CosIng · EWG · CIR