Polyquaternium-53

Polyquaternium-53 molecular structure
molecular structure · PubChem
Synthetic
Skin Conditioner
Hair Care
Not Clean
Acrylic acid/acrylamide/methacrylamidopropyltrimonium chloride copolymer
CAS #
84647-38-1
Form
Liquid
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Hair
Softens and detangles hair
Traditional Use
A modern synthetic polymer created as a conditioning and antistatic agent for cosmetics. Developed to provide improved hair and skin conditioning properties compared to earlier polymer formulations.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR