Polyquaternium-53

Synthetic

Skin Conditioner

Hair Care

Not Clean

OriginSynthesized from acrylic monomers and quaternary ammonium compounds through polymerization reactions. Produced by cross-linking polymers with quaternizing agents to create a positively charged conditioning polymer.

Acrylic acid/acrylamide/methacrylamidopropyltrimonium chloride copolymer

CAS #

84647-38-1

Form

Liquid

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

Functions

Hair Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Conditions Hair

Softens and detangles hair

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed2 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

EWG

CIR

Safe as used

Pregnancy

Yes

Concentration Guide

CIR lists it as not reported to be in use.

CIR · report published 2012

Regulatory Status

USA✔ permitted

EU✔ permitted

JAPAN✔ permitted

CANADA✔ permitted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Verified Jun 2026

Data: CosIng · EWG · CIR