murphyPolyquaternium-6
molecular structure · PubChem
AKA: Polyquaternium 6
Synthetic
Occlusive
Clean
OriginSynthesized from acrylamide and dimethylaminopropyl chloride, belonging to the quaternary ammonium polymer family. Produced through free-radical polymerization of these monomers to create a positively charged polymer chain.
Polyquaternium-6 is a polymeric quaternary ammonium salt of dimethyl diallyl ammonium chloride
CAS #
26062-79-3
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Reduces Static
Creates Protective Barrier
Fights Bacteria
Creates protective layer
Reduces flyaways
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
Human test found no phototoxicity in the CIR safety assessment (CIR 826)
Not a Sensitizer
3 studies / 3 not sensitizing (CIR 826)
Mixed Skin Irritation Results
6 studies / 2 irritating / 1 mixed / 3 not irritating / reactions slight to severe (CIR 826)
Mixed Eye Irritation Results
3 studies / 2 irritating / 1 not irritating / reactions slight (CIR 826)
Concentration Guide
Leave-on0.0004–1.2%
Rinse-off0.04–3%
0%50%100%
CIR reported use · 2020 survey
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR