murphyPolyquaternium-61
molecular structure · PubChem
AKA: Polyquaternium 61
Synthetic
Occlusive
Skin Conditioner
Clean
OriginSynthesized from acrylic monomers including methyl methacrylate and quaternary ammonium compounds as the chemical starting materials. Produced through free-radical polymerization of the monomers to create the cationic polymer chain structure.
2-Methyl-2-propenoyloxyethyl N,N,N-trimethylammonioethyl phosphate inner salt, polymer with octadecyl 2-methyl-2-propenoate
CAS #
-
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 820)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2022
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR