Polyurethane-50

Polyurethane-50 molecular structure
molecular structure · PubChem
AKA: Polyurethane polymer, Film-forming agent
Synthetic
Skin Conditioner
Not Clean
OriginSynthesized from poly(1,4-butanediol), aromatic isocyanates, and ethoxylated bisphenol A with acrylate monomers. Produced through step-growth polymerization combining isocyanate and hydroxyl group reactions.
Polyurethane-50 is a copolymer of poly(1,4-butanediol)l, 1,3-bis(isocyanatomethyl)benzene, ethoxylated 4,4'-isopropylidenediphenol and 4-hydroxyethyl acrylate
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Nail Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens nails
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR