Polyurethane-54

Polyurethane-54 molecular structure
molecular structure · PubChem
Synthetic
Skin Conditioner
Not Clean
OriginPolyurethane-54 belongs to the polyurethane polymer chemical family, synthesized from petrochemical-derived polyols and isocyanates. It is produced through the polymerization reaction of these precursors, creating a flexible polymer chain structure.
Polyurethane-54 is a copolymer of poly(1,4-butanediol)-4, 1,2-butanediol, 3-(acryloyloxy)-2-hydroxypropyl methacrylate and isophorone diisocyanate.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Nail Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens nails
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR