Polyurethane-60

Synthetic
Skin Conditioner
Not Clean
Polyurethane-60 is the complex polymer made by first reacting saturated methylene diphenyldiisocyanate (SMDI), dimethyl aminopropylamine (DMAPA), isopropylidenediphenoxypropanol, and dimethylcarbonate-1,6-hexanediol to form a prepolymer, followed by dispersion in water with dimethylethanolamine and subsequent chain extension with ethylenediamine.
Functions
Nail Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Strengthens nails
Traditional Use
A synthetic polymer developed in the mid-20th century for industrial applications. Used in cosmetics as a film-forming agent and texture modifier in formulations like foundations and primers.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR