Polyurethane-66

Synthetic

Not Clean

Polyurethane-66 is a urethane polymer formed by reacting a polymer of 1,4-butanediol that contains an average of 28 moles of butylene oxide with a combination of isophorone diisocyanate (IPDI) and 1,3-bis(isocyanomethyl)cyclohexane. The polymer is end-blocked with hydroxybutyl acrylate.

Form

Powder

Functions

Binding

Holds Formula Together

Holds ingredients together

Traditional Use

A synthetic polymer developed in the mid-20th century for industrial applications. Used in cosmetics as a film-forming agent and texture modifier in formulations like foundations and primers.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not a Sensitizer

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: CosIng · EWG · CIR