Potassium Glycyrrhizinate

AKA: Alpha-D-Glucopyranosiduronic acid, Potassium salt (1:?), .alpha.-D-Glucopyranosiduronic acid, Glycyrrhizinic acid, Potassium salt, 68039-19-0, 42294-03-1, Potassium;(2S, 3S, 4S, 5R, 6S)-6-[[(3S, 4aR, 6aR, 6bS, 8aS, 11S, 12aR, 14aR, 14bS)-11-carboxy-4, 4, 6a, 6b, 8a, 11, 14b-heptamethyl-14-oxo-2, 3, 4a, 5, 6, 7, 8, 9, 10, 12, 12a, 14a-dodecahydro-1H-picen-3-yl]oxy]-5-[(2R, 3R, 5S, 6S)-6-carboxy-3, 5-trihydroxyoxan-2-yl]oxy-3, 4-dihydroxyoxane-2-carboxylate

Synthetic

Skin Conditioner

Not Clean

.alpha.-D-Glucopyranosiduronic acid, (3-.beta.-,20-.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-.beta.-D-glucopyranuronosyl-, potassium salt

Formula

C42H61KO16

Mol. Weight

861.00

CAS #

68039-19-0

Form

Powder

Functions

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Locks in moisture

Traditional Use

Extracted from licorice root (Glycyrrhiza glabra), a plant used for over 3,000 years in Ayurvedic, Traditional Chinese, and Greek medicine for skin inflammation and irritation. The potassium salt was developed to enhance stability and solubility in cosmetic formulations.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not an Irritant

medical-approval

all-shades-safe

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

Redness

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed2 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: PubChem · CosIng · EWG · CIR