PPG-20 Methyl Glucose Ether
molecular structure · PubChem
AKA: Methyl glucoside propoxylate, 61849-72-7, 612-557-2, 3-[[(2S, 3S, 4R, 5S, 6S)-3, 4, 5-tris(3-hydroxypropoxy)-6-methoxyoxan-2-yl]methoxy]propan-1-ol, GCNUSOSMERSJBN-OYSTVDSJSA-N
Synthetic
Skin Conditioner
Hair Care
Clean
OriginDerived from glucose and plant-derived propylene glycol polymers as starting materials. Synthesized through etherification and polymerization reactions combining glucose with PPG chains.
Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1)
Formula
C19H38O10
Mol. Weight
426.50
CAS #
61849-72-7
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
2 studies / 2 not irritating (CIR 617)
Not a Sensitizer
1 study / 1 not sensitizing / plus 1 case report (CIR 617)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 617)
Concentration Guide
Leave-on0.1–3%
Rinse-off0.1–0.5%
0%50%100%
CIR reported use · 2013 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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