Propionyl Collagen Amino Acids

AKA: Hydrolyzed Collagen Propionate
Synthetic
Skin Conditioner
Marine
Amino Acid
Acid
Not Clean
Condensation product of propionic acid chloride with collagen amino acids
CAS #
210545-23-6; 616-91-1; 1188-37-0; 2490-97-3; 35305-74-9
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Locks in moisture
Traditional Use
Developed in the late 20th century as a modified protein derivative. Created as a film-forming and conditioning agent for skincare and haircare products, designed to mimic collagen's moisturizing properties.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed1 review
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR