Propionyl Collagen Amino Acids

AKA: Hydrolyzed Collagen Propionate

Synthetic

Skin Conditioner

Amino Acid

Acid

Not Clean

Origin-Derived (bovine/marine) or Biotech

Condensation product of propionic acid chloride with collagen amino acids

CAS #

210545-23-6; 616-91-1; 1188-37-0; 2490-97-3; 35305-74-9

Skin Types

●all-skin-types

Best For

Loss of Elasticity

Pregnancy & Breastfeeding Safe

Yes

Functions

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Boosts collagen production

Locks in moisture

The paper trail

🔬Peer-reviewed1 paper →

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

EWG

CIR

Safe as used

Pregnancy

Yes

Concentration Guide

CIR lists it as not reported to be in use.

CIR · report published 2017

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

Verified Jun 2026

Data: CosIng · EWG · CIR