Propyl Glycolate

AKA: Acetic acid, Propyl ester, 90357-58-7, Glycolic acid, NORCOOJYTVHQCR-UHFFFAOYSA-N, Hydroxyacetic acid propyl ester, Propyl 2-Hydroxyacetic Acid Ester
Synthetic
Skin Conditioner
Not Clean
OriginPropyl glycolate is synthesized from glycolic acid, an alpha hydroxy acid (AHA) derived from sugarcane processing. It is produced through esterification of glycolic acid with propanol via acid-catalyzed condensation reactions.
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Propyl Glycolate...
Formula
C5H10O3
Mol. Weight
118.13
CAS #
90357-58-7
Form
Liquid
Skin Types
●all-skin-types
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Shields from UV damage
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR