Propylene Glycol Diisostearate

Propylene Glycol Diisostearate molecular structure
molecular structure · PubChem
AKA: 68958-54-3, Isooctadecanoic acid, 1-methyl-1, 2-ethanediyl ester, 1'-(1-methyl-1, 2-ethanediyl) ester, 1-Methyl-1, 2-ethanediyl diisooctadecanoate, Propane-1, 2-diyl bis(16-methylheptadecanoate), 2-(16-methylheptadecanoyloxy)propyl 16-methylheptadecanoate
Plant-Derived
Emollient
Skin Conditioner
Plant Oil
Not Clean
1-Methyl-1,2-ethanediyl diisooctadecanoate
Effective at 1.0%
Formula
C39H76O4
Mol. Weight
609.00
CAS #
68958-54-3
Form
Liquid
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Developed in the late 20th century as a propylene glycol diester of isostearic acid. Used in contemporary cosmetics as an emollient and thickening agent, designed to provide conditioning similar to natural fatty acids with improved stability.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
9.9e-05%
2.0%
0%14%
Reported use
CIR reported use: 0.000099-2
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR