Quassin

Quassin molecular structure
molecular structure · PubChem
AKA: 76-78-8, (+)-Quassin, (1S, 2S, 6S, 7S, 9R, 13R, 17S)-4, 15-dimethoxy-2, 6, 14, 17-tetramethyl-10-oxatetracyclo[7.7.1.02, 7.013, 17]heptadeca-4, 14-diene-3, 11, 16-trione, Picrasa-2, 12-diene-1, 17-tetramethyl-10-oxatetracyclo(7.7.1.02, 17)heptadeca-4
Synthetic
Not Clean
(3aS,6aR,7aS,8S,11aS,11bS,11cS)-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-Dodecahydro-2,10-dimethoxy-3,8,11a,11c-tetramethyldibenzo[de,g]chromene-1,5,11-trione
Formula
C22H28O6
Mol. Weight
388.50
CAS #
76-78-8, 75991-65-0
Form
Liquid
Functions
Denaturant
Makes Alcohol Undrinkable
Fights Bacteria
Antioxidant Protection
Reduces Inflammation
Traditional Use
Quassin is a bitter compound extracted from quassia wood, which has been used in traditional medicine in the Caribbean and South America for its antimicrobial and anti-parasitic properties. It has been incorporated into modern skincare for potential skin-clarifying benefits.
EWG
5
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR