Rhamnose

AKA: 6-Deoxy-L-mannopyranose, (3R, 4R, 5R, 6S)-6-methyloxane-2, 3, 4, 5-tetrol, 6-deoxy-Mannose, Isodulcit, 6-Deoxy-Mannopyranose, 6-deoxy-mannopyranoside, 6-Deoxy-L-Mannopyranoside, CHEBI:16055, CHEBI:62345
Synthetic
Humectant
Sugar-Based Active
Clean
OriginRhamnose is a deoxy sugar synthesized from natural plant sources including glucose or mannose through chemical reduction and isomerization processes. It is produced via catalytic hydrogenation and selective chemical modification of hexose sugars in controlled laboratory conditions.
A methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides.
Formula
C6H12O5
Mol. Weight
164.16
CAS #
3615-41-6, 10030-85-0
Form
Powder
State
Solid
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
1 study / 1 not sensitizing (CIR 657)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 not irritating (CIR 657)
Concentration Guide
Leave-on5–10%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2019
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR