Saccharide Isomerate
AKA “Carbohydrate polymer, Humectant
Humectant
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Ingredient Facts
Saccharide isomerate
AKA: Carbohydrate polymer, Humectant
Humectant · Humectant · EWG: 1
Synthetic
Humectant
Amino Acid
Clean
Saccharides, isomerised
CAS #
100843-69-4
Form
Liquid
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
A modern humectant ingredient developed in the late 20th century through chemical isomerization of sugars. Designed to improve skin hydration and texture in contemporary skincare formulations.
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
Dermal absorption: 100%. Source: CIR Safety Assessment (CIR Seq 815).
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
AM + PM Hydrating Booster Set
Goldfaden MD
 →
Balance + Support Duo
Marie Veronique
 →
Bonne Nuit™ Night Cream
Pai Skincare
 →
ceramide hydration duo
Cocokind
 →
Clearing Mask
Indie Lee
 →
Smooth + Sculpt Set
Grown Alchemist
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Detox & Clarify Collection
Goldfaden MD
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Detox Hydrating Gel
Goldfaden MD
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BB Burst
Kosas
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milky-soft face and body cleanser
Cocokind
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Phaze™ Gel Cleanser
Pai Skincare
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Phaze™ Gel Cleanser Mini
Pai Skincare
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Resurrection Girl™ Mask
Pai Skincare
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retinol face + body duo
Cocokind
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Skin Renewal Serum (25mL)
Grown Alchemist
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[Travel Size] Skin Renewal Serum (5mL)
Grown Alchemist
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Regenerating Gel Mask
Credo Beauty
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Regenerating Gel Mask (20ml)
Grown Alchemist
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The Cleanse Soft Foaming Cleanser
ILIA Beauty
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Tinted Skincare Lineup with BB Burst
Credo Beauty
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Barrier Restore Serum
Marie Veronique
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COLORFREE Zinc Broad Spectrum Sunscreen SPF 32
Credo Beauty
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COLORFREE ZINC Broad Spectrum Sunscreen | SPF 32
Marie Veronique
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Gentle Retinol Night Serum
Marie Veronique
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The Body Wash | Multi-Oil
Credo Beauty
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Advanced Protection Cream
OSEA
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Advanced Protection Cream - 0.25 oz
OSEA
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Anti-Aging Sea Serum - 0.19 fl oz
OSEA
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Atmosphere Protection®Cream
OSEA
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Atmosphere Protection®Cream - 0.6 fl oz
OSEA
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Brightening Eye Gel 3mL
Credo Beauty
 →
Brightening Eye Gel 3mL – Tata Harper Skincare
Tata Harper Skincare
 →
Clarifying Cleanser - 15ML
Credo Beauty
 →
Clarifying Cleanser - 15ML – Tata Harper Skincare
Tata Harper Skincare
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Clarifying Cleanser
Tata Harper Skincare
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Clarifying Cleanser CA
Credo Beauty
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Concentrated Brightening Essence
Tata Harper Skincare
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Crème Riche - 7.5ML
Credo Beauty
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Crème Riche
Tata Harper Skincare
 →
Elixir Vitae Eye Serum
Tata Harper Skincare
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Hydrating Floral Essence - 15ML
Credo Beauty
 →
Hydrating Floral Essence - 15ML – Tata Harper Skincare
Tata Harper Skincare
 →
Hydrating Floral Essence
Tata Harper Skincare
 →
Hydrating Floral Mask - 5ML
Credo Beauty
 →
Hydrating Floral Mask - 5ML – Tata Harper Skincare
Tata Harper Skincare
 →
Hydrating Floral Mask
Tata Harper Skincare
 →
Refillable Restorative Eye Crème
Tata Harper Skincare
 →
Rejuvenating Serum - 10ML
Tata Harper Skincare
 →
Repairative Moisturizer - 10ML
Credo Beauty
 →
Repairative Moisturizer - 10ML – Tata Harper Skincare
Tata Harper Skincare
 →
Safety Assessment of Anhydrogalactose,Anhydroglucitol, Anhydroxylitol, Arabinose,Psicose, Saccharide Hydrolysate, andSaccharide Isomerate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Saccharide Isomerate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Saccharide Isomerate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population.
Martin E, Zhang A, Campiche R
Journal of cosmetic dermatology, 2023
Verified Jun 2026
Data: CosIng · EWG · CIR