murphySerine
AKA: L-serine, 56-45-1, (S)-2-Amino-3-hydroxypropanoic acid, (S)-Serine, Beta-Hydroxyalanine, L-(-)-Serine, L-ser, (2S)-2-amino-3-hydroxypropanoic acid, Serina
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
OriginSynthesized from organic compounds belonging to the amino acid chemical family through laboratory processes. Produced via fermentation of glucose using genetically modified microorganisms or chemical synthesis methods.
2-Amino-3-hydroxypropanoic acid
Solubility 425000
Formula
C3H7NO3
Mol. Weight
105.09
CAS #
302-84-1, 56-45-1
Form
Powder
State
Solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
4 studies / 4 not irritating (CIR 607)
Not a Sensitizer
3 studies / 3 not sensitizing (CIR 607)
Eye Irritant in Testing
1 study / 1 irritating / reactions weak (CIR 607)
Concentration Guide
Leave-on0.00003–2%
Rinse-off0.0002–1%
0%50%100%
CIR reported use · 2012 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR