Silybum marianum ethyl ester
AKA: Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Plant-Derived Synthetic
Skin Conditioner
Not Clean
Silybum Marianum Ethyl Ester is the ethyl ester of the fatty acids derived from the oil of the Lady's Thistle, Silybum marianum (L.), Asteraceae
CAS #
84604-20-6
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Milk thistle (Silybum marianum) has been used in European and traditional medicine since ancient Greece for liver and skin health. The ethyl ester form is a modern extraction designed to preserve the plant's active silymarin compounds.
Skin Types
●all-skin-types
Best For
Irritation
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed0 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR