sodium anisate
AKA “536-45-8, sodium p-anisate, sodium p-methoxybenzoate, UNII-F9WFJ28MV9, F9WFJ28MV9, Benzoic acid, 4-methoxy-, sodium salt, EINECS 208-634-1, DTXSID00201818, RefChem:183779
Ingredient
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Ingredient Facts
Sodium anisate
AKA: 536-45-8, Sodium p-anisate, Sodium p-methoxybenzoate, UNII-F9WFJ28MV9, F9WFJ28MV9, Benzoic acid, 4-methoxy-, Sodium salt, EINECS 208-634-1, DTXSID00201818, RefChem:183779
Ingredient · Antimicrobial · EWG: 1
Synthetic
Preservative
Safety Concern
Clean
Sodium anisate
Formula
C8H7NaO3
Mol. Weight
174.13
CAS #
536-45-8
Form
Powder
See origin →
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Flavouring
Ph Adjusters
Fights Bacteria
Traditional Use
A synthetic preservative developed in the 20th century derived from anise (anethole); created to provide antimicrobial protection in cosmetics as a safer alternative to older chemical preservatives.
Skin Types
all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
ewg-1
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Age-Defying Fundamentals
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Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of 4-Methoxy-m-Phenylenediamine, 4-Methoxy-m-Phenylenediamine Sulfate, and 4-Methoxy-m-Phenylenediamine-HCI
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
sodium anisate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
sodium anisate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
SODIUM SALT
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
4-Methoxy-m-phenylenediamine and its sulfate salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
4-Methoxy-m-phenylenediamine-HCl
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR