Sodium Lauroamphoacetate

AKA: 66161-62-4, Glycine, Monosodium salt, Sodium salt (1:1), Sodium;2-[2-(dodecanoylamino)ethyl-(2-hydroxyethyl)amino]acetate, COLATERIC SLAA, MIRANOL HMA
Synthetic
Cleanser
Skin Conditioner
Hair Care
Clean
OriginDerived from coconut or palm kernel oils through fatty acid extraction and purification of lauric acid sources. Synthesized by amidation of lauric acid with dimethylaminopropionic acid, followed by acetylation.
Glycine, N-(2-hydroxyethyl)-N-[2-(1-oxododecylamino)ethyl]-, monosodium salt
Formula
C18H35N2NaO4
Mol. Weight
366.50
CAS #
66161-62-4
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foaming
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Removes Impurities
Creates Lather
Conditions Hair
Cleansing Surfactant
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Reviewed by CIR
Pregnancy
Yes
CIR Safety Findings
Mixed Skin Irritation Results
7 studies / 2 irritating / 1 mixed / 4 not irritating / reactions slight to severe / plus 1 case report (CIR 886)
Mixed Sensitization Results
4 studies / 1 mixed / 3 not sensitizing / plus 2 case reports (CIR 886)
Mixed Eye Irritation Results
4 studies / 2 irritating / 1 mixed / 1 not irritating / reactions slight to severe (CIR 886)
Concentration Guide
Leave-on2.1%
Rinse-off0.8–7.1%
0%50%100%
CIR reported use · 2025 survey
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR