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sodium levulinate
AKA “19856-23-6, Pentanoic acid, 4-oxo-, sodium salt, VK44E1MQU8, DTXSID60173608, LEVULINIC ACID, SODIUM SALT, RefChem:183967, DTXCID2096099, 243-378-4, Sodium 4-oxovalerate”
Skin Conditioning
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Ingredient Facts
Sodium levulinate
AKA: 19856-23-6, Pentanoic acid, 4-oxo-, Sodium salt, VK44E1MQU8, DTXSID60173608, LEVULINIC ACID, SODIUM SALT, RefChem:183967, DTXCID2096099, 243-378-4, Sodium 4-oxovalerate
Skin Conditioning · Miscellaneous · EWG: 1
Synthetic
Skin Conditioner
Clean
Sodium 4-oxovalerate
Formula
C5H7NaO3
Mol. Weight
138.10
CAS #
19856-23-6
Form
Powder
See origin →
Functions
Miscellaneous
Skin Conditioning Miscellaneous
Improves skin feel
Traditional Use
A modern synthetic preservative developed as part of the clean beauty movement to replace parabens, derived from levulinic acid and designed to inhibit microbial growth in cosmetic products.
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Phototoxicity Concern
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Age-Defying Fundamentals
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Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
levulinic acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
sodium levulinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
levulinic acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
sodium levulinate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
SODIUM SALT
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Physicochemical and safety evaluation of 5-aminolevulinic acid in novel liposomes as carrier for skin delivery.
Fang YP, Wu PC, Tsai YH, Huang YB
Journal of liposome research, 2008
→
Physicochemical and safety evaluation of 5-aminolevulinic acid in novel liposomes as carrier for skin delivery.
Fang YP, Wu PC, Tsai YH, Huang YB
Journal of liposome research, 2008
→
Safety Assessment of Levulinic Acid and Sodium Levulinate as Used in Cosmetics.
Raj PS, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
→
Oil components modulate the skin delivery of 5-aminolevulinic acid and its ester prodrug from oil-in-water and water-in-oil nanoemulsions.
Zhang LW, Al-Suwayeh SA, Hung CF, Chen CC, Fang JY
International journal of nanomedicine, 2011
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR