Sodium Mannose Phosphate

AKA: 70442-25-0, Sodium mannose 6-phosphate, Sodium D-mannose 6-phosphate, D-Mannose, 6-(dihydrogen phosphate), Sodium salt (1:1), Monosodium salt, D-Mannose-6-phosphate sodium salt, Sodium;[(2R, 3R, 4S, 5S)-2, 3, 4, 5-tetrahydroxy-6-oxohexyl] hydrogen phosphate
Synthetic
Humectant
Skin Conditioner
Marine
Clean
Sodium salt of a complex mixture of esters of phosphoric acid and Mannose
Formula
C6H12NaO9P
Mol. Weight
282.12
CAS #
70442-25-0
Form
Powder
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
Developed in the late 20th century as a modern humectant and skin-conditioning agent derived from mannose (a simple sugar), created to provide moisture-binding properties in contemporary skincare formulations.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR