Sodium Mannose Phosphate

Sodium Mannose Phosphate 1
molecular structure · PubChem CID 23681585
AKA: 70442-25-0, Sodium mannose 6-phosphate, Sodium D-mannose 6-phosphate, D-Mannose, 6-(dihydrogen phosphate), Sodium salt (1:1), Monosodium salt, D-Mannose-6-phosphate sodium salt, Sodium;[(2R, 3R, 4S, 5S)-2, 3, 4, 5-tetrahydroxy-6-oxohexyl] hydrogen phosphate
Synthetic
Humectant
Skin Conditioner
Clean
OriginSodium mannose phosphate is synthesized from mannose, a simple sugar derived from plant sources like seaweed or cellulose. It is produced through phosphorylation of mannose, followed by neutralization with sodium hydroxide to form the salt.
Sodium salt of a complex mixture of esters of phosphoric acid and Mannose
Formula
C6H12NaO9P
Mol. Weight
282.12
CAS #
70442-25-0
Form
Powder
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 759)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 759)
Not an Eye Irritant
1 study / 1 not irritating (CIR 759)
Concentration Guide
Leave-on0.1%
Rinse-offNot reported
0%50%100%
CIR reported use · 2017 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR