Sodium Octoxynol-2 Sulfate

AKA: Triton X-301, 12627-38-2, Sodium;2-[4-(2, 4, 4-trimethylpentan-2-yl)phenoxy]ethyl sulfate, Sodium 2-[4-(2
Synthetic
Cleanser
Not Clean
OriginDerived from octylphenol ethoxylates, a class of nonionic surfactant compounds synthesized from petrochemical sources. Produced through ethoxylation of octylphenol followed by sulfation to create the anionic surfactant product.
Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-, sodium salt
Formula
C16H25NaO5S
Mol. Weight
352.40
CAS #
12627-38-2
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foaming
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Surfactant Cleansing
Anti-Inflammatory
Antimicrobial
Fights Acne
Removes dirt and impurities
Creates cleansing foam
Lifts away dirt and oil
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2025
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR