Sodium Octoxynol-2 Sulfate

AKA: Triton X-301, 12627-38-2, Sodium;2-[4-(2, 4, 4-trimethylpentan-2-yl)phenoxy]ethyl sulfate, Sodium 2-[4-(2
Synthetic
Cleanser
Not Clean
Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-, sodium salt
Formula
C16H25NaO5S
Mol. Weight
352.40
CAS #
12627-38-2
Form
Powder
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foaming
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Surfactant Cleansing
Anti-Inflammatory
Antimicrobial
Fights Acne
Removes dirt and impurities
Creates cleansing foam
Lifts away dirt and oil
Traditional Use
A synthetic surfactant combining octoxynol chemistry with sulfate functionality. Developed as a gentler alternative to sodium lauryl sulfate for personal care applications.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Mild Irritant
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR