Sodium Palmitoyl Proline

AKA: 58725-33-0, Sodium 5-oxo-1-palmitoyl-L-prolinate, N-Palmitoyl-L-proline sodium salt, SODIUM PALMITOYL PROLINE [WHO-DD], SODIUM PALMITOYL PROLINE [INCI]
Synthetic
Skin Conditioner
Amino Acid
Synthetic
Clean
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Sodium Palmitoyl Proline...
Formula
C21H38NNaO3
Mol. Weight
375.50
CAS #
58725-33-0
Form
Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Softens & Smooths
Traditional Use
Unable to provide traditional use description without a valid INCI or common name; this appears to be a CAS number without corresponding ingredient information.
EWG
1
CIR
Insufficient
Pregnancy
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Skin Types
all-skin-types
Best For
General
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR