Sodium Palmitoyl Proline

AKA: 58725-33-0, Sodium 5-oxo-1-palmitoyl-L-prolinate, N-Palmitoyl-L-proline sodium salt, SODIUM PALMITOYL PROLINE [WHO-DD], SODIUM PALMITOYL PROLINE [INCI]
Synthetic
Skin Conditioner
Amino Acid
Synthetic
Clean
OriginDerived from the amino acid proline and palmitic acid, both obtainable through synthetic or natural sources. Synthesized through condensation and esterification reactions linking palmitic acid to proline's nitrogen atom.
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Sodium Palmitoyl Proline...
Formula
C21H38NNaO3
Mol. Weight
375.50
CAS #
58725-33-0
Form
Powder
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Softens & Smooths
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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