Sodium Salicylate

Sodium Salicylate 1
molecular structure · PubChem CID 16760658
AKA: 54-21-7, Enterosalicyl, Kerasalicyl, Alysine, Benzoic acid, Monosodium salt, Natrum salicylicum, Salicylate sodium, Salicylic acid sodium salt, Monosodium 2-hydroxybenzoate
Synthetic
Skin Conditioner
Synthetic
Clean
OriginDerived from salicylic acid, a beta hydroxy acid compound synthesized from petroleum-based or coal tar feedstock. Produced through neutralization of salicylic acid with sodium hydroxide or sodium carbonate.
A non-steroidal anti-inflammatory agent that is less effective than equal doses of ASPIRIN in relieving pain and reducing fever. However, individuals who are hypersensitive to ASPIRIN may tolerate sodium salicylate. In general, this salicylate produces the same adverse reactions as ASPIRIN, but there is less occult gastrointestinal bleeding. (From AMA Drug Evaluations Annual, 1992, p120)
Formula
C7H5NaO3
Mol. Weight
160.10
CAS #
54-21-7
Form
Liquid
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Makes Alcohol Undrinkable
Preserves Formula
Prevents microbial growth
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 766)
Eye Irritant in Testing
2 studies / 2 irritating / reactions mild (CIR 766)
Concentration Guide
Leave-on0.0015–0.1%
Rinse-off0.0008–0.5%
0%50%100%
Reg. limit 0.5%
CIR reported use · 2018 survey
EU regulatory limit: 0.5%. Not to be used for children under 3 years of age (2) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 3.
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR