Sodium Xylenesulfonate

AKA: Naxonate, Hydrotrope, Xylenesulfonic Acid Sodium Salt, Stepanate X, Naxonate G, Richonate SXS, Cyclophil sxs30, Conco SXS, Surco SXS
Synthetic
Cleanser
Not Clean
OriginSynthesized from xylene (a petroleum-derived aromatic hydrocarbon) and sulfonic acid derivatives within the alkylbenzene sulfonate chemical family. Produced through sulfonation of xylene isomers followed by neutralization with sodium hydroxide or sodium carbonate.
Sodium Xylenesulfonate ... safe as cosmetic ingredient in the present practice of use and concentration as described in this safety assessment, when formulated to be nonirritating
Solubility greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Formula
C8H9NaO3S
Mol. Weight
208.21
CAS #
1300-72-7
Form
Liquid
State
Xylenesulfonic acid, sodium salt is an odorless white crystalline powder. (NTP, 1992)
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hydrotrope
Surfactant Hydrotrope
Locks In Moisture
Improves ingredient solubility
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Eye Irritant in Testing
1 study / 1 irritating / reactions slight (CIR 496)
Skin Irritant in Testing
4 studies / 4 irritating / reactions slight (CIR 496)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR