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Sorbitan Triisostearate
AKA “Sorbitan, triisooctadecanoate, 54392-27-7, P3ZV48C8J1, RefChem:888290, DTXSID50969512, SORBITAN TRIISOSTEARATE [INCI], 259-141-3, [(3S, 4R, 5R)-5-[(1R)-2-hydroxy-1-(16-methylheptadecanoyloxy)ethyl]-4-(16-methylheptadecanoyloxy)oxolan-3-yl] 16-methylheptadecanoate, Anhydrosorbitol triisostearate”
Surfactant
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Ingredient Facts
Sorbitan triisostearate
AKA: Triisooctadecanoate, 54392-27-7, P3ZV48C8J1, RefChem:888290, DTXSID50969512, SORBITAN TRIISOSTEARATE [INCI], 259-141-3, [(3S, 4R, 5R)-5-[(1R)-2-hydroxy-1-(16-methylheptadecanoyloxy)ethyl]-4-(16-methylheptadecanoyloxy)oxolan-3-yl] 16-methylheptadecanoate, Anhydrosorbitol triisostearate
Surfactant · Emulsifying · EWG: 4
Plant-Derived
Cleanser
Emulsifier
Plant Oil
Not Clean
Sorbitan, triisooctadecanoate
Formula
C60H114O8
Mol. Weight
963.50
CAS #
54392-27-7
See origin →
Functions
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Emulsifying
Improves Elasticity
Moisturizing
Boosts Collagen
Mixes oil and water
Traditional Use
A synthetic emulsifier created from sorbitol and isostearic acid. Developed for use in cosmetics to improve the stability and sensory feel of creams and lotions.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Final Repoort on the Safety Assessment of PEG-6, -8, -20 Sorbitan Beeswax
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of PEG-20 Sorbitan Cocoate; PEG-40 Sorbitan Diisostearate; PEG-2, -5, and -20 Sorbitan Isostearate; PEG-40 and -75 Sorbitan Lanolate; PEG-10, -40, -44, -75, and -
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Sorbitan Caprylate, Sorbitan Cocoate, Sorbitan Diisostearate, Sorbitan Dioleate, Sorbitan Distearate, Sorbitan Isostearate, Sorbitan Olivate, Sorbitan Sesquiis
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Sorbitan Stearate, Sorbitan Laurate, Sorbitan Sesquioleate, Sorbitan Oleate, Sorbitan Tristearate, Sorbitan Palmitate, and Sorbitan Trioleate (Addended by repo
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Sorbitan Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
PEG-10 Sorbitan Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-160 Sorbitan Triisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-2 Sorbitan Isostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-2 Sorbitan Trioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Sorbitan Cocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Sorbitan Isostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Sorbitan Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-20 Sorbitan Triisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-3 Sorbitan Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-3 Sorbitan Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-3 Sorbitan Tristearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-30 Sorbitan Tetraoleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-4 Sorbitan Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-4 Sorbitan Triisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Diisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Lanolate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Perisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Peroleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-40 Sorbitan Tetraoleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-44 Sorbitan Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-5 Sorbitan Isostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-6 Sorbitan Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-6 Sorbitan Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-60 Sorbitan Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-60 Sorbitan Tetraoleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-60 Sorbitan Tetrastearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-75 Sorbitan Lanolate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-75 Sorbitan Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-80 Sorbitan Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-80 Sorbitan Palmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Caprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Cocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Diisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Dioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan olivate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Palmate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Sesquicaprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Sesquiisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Sesquistearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Triisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Trioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sorbitan Undecylenate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-10 Sorbitan Laurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Sorbitan Beeswax
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Sorbitan Cocoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Sorbitan Isostearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-20 Sorbitan Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-3 Sorbitan Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-3 Sorbitan Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-30 Sorbitan Tetraoleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-4 Sorbitan Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-40 Sorbitan Perisostearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-40 Sorbitan Peroleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-40 Sorbitan Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-6 Sorbitan Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-6 Sorbitan Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-60 Sorbitan Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-80 Sorbitan Laurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Caprylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Cocoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Laurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Oleate Decylglucoside
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan olivate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Palmitate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Sesquicaprylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Sesquiisostearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Sesquioleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Sesquistearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Trioleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sorbitan Tristearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Safety Assessment of Sorbitan Esters as Used in Cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2019
→
Safety Assessment of Sorbitan Esters as Used in Cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2019
→
Safety Assessment of Sorbitan Esters as Used in Cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2019
→
Clinical preliminary evaluation of PEG-80 sorbitan laurate (Novisol) versus sodium C14-16 olefin sulfonate & triclosan (Septisol) in deep-peeling Hett
Kass LG, Rullan PP, Brody HJ
Journal of the American Academy of Dermatology, 2020
→
Clinical preliminary evaluation of PEG-80 sorbitan laurate (Novisol) versus sodium C14-16 olefin sulfonate & triclosan (Septisol) in deep-peeling Hett
Kass LG, Rullan PP, Brody HJ
Journal of the American Academy of Dermatology, 2020
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-6, -8, and -20 sorbitan beeswax.
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of sorbitan caprylate, sorbitan cocoate, sorbitan diisostearate, sorbitan dioleate, sorbitan distearate, sorbita
Lanigan RS, Yamarik TA, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Management of hot tar burn using vitamin e ointment containing petroleum and polyoxyethylene sorbitan.
Ng K, Dalen D, Rhine D
CJEM, 2013
→
Physicochemical characterization of sodium stearoyl lactylate (SSL), polyoxyethylene sorbitan monolaurate (Tween 20) and κ-carrageenan.
Ortiz-Tafoya MC, Tecante A
Data in brief, 2018
→
Development and characterization of topical formulation for maintenance therapy containing sorbitan monostearate with and without PEG-100-stearate.
Schoenfelder H, Wiedemann Y, Lunter DJ
International journal of cosmetic science, 2025
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR