Stearamidopropyl Dimethylamine

AKA: 7651-02-7, N-[3-(Dimethylamino)propyl]octadecanamide, Octadecanamide, Incromine sd, Dimethylaminopropyl stearamide, Mackine 301, JEECHEM S-13
Plant-Derived
Cleanser
Emulsifier
Skin Conditioner
Hair Care
Not Clean
OriginDerived from coconut or palm oil-based fatty amines and dimethylamine compounds. Synthesized through amidation and dimethylation reactions of stearic acid derivatives with dimethylamine.
N-[3-(Dimethylamino)propyl]stearamide
Formula
C23H48N2O
Mol. Weight
368.60
CAS #
7651-02-7
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Improves Elasticity
Lifts away dirt and oil
Reduces flyaways
Softens and detangles hair
Mixes oil and water
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
6
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Skin Irritation Results
4 studies / 2 irritating / 2 not irritating / reactions mild (CIR 616)
Mixed Sensitization Results
5 studies / 1 sensitizing / 4 not sensitizing (CIR 616)
Mixed Eye Irritation Results
1 study / 1 mixed / reactions severe (CIR 616)
Concentration Guide
Leave-on0.02–3%
Rinse-off0.01–5%
0%50%100%
CIR reported use · 2012 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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