Stearoyl Leucine

AKA: 14379-43-2, (2S)-4-methyl-2-(octadecanoylamino)pentanoic acid, N-Octadecanoylleucine, N-Stearoyl-L-leucine, N-octadecanoyl-L-leucine, L-Leucine
Plant-Derived
Cleanser
Emulsifier
Skin Conditioner
Hair Care
Not Clean
OriginDerived from amino acids, particularly leucine, combined with stearic acid or stearoyl chloride. Synthesized through esterification or acylation of leucine with stearic acid derivatives.
L-Leucine, N-(1-oxooctadecyl)-
Formula
C24H47NO3
Mol. Weight
397.60
CAS #
14379-43-2
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR