Sucralose

AKA: 56038-13-2, Splenda, Trichlorosucrose, Aspasvit, Sucrazit, Trichlorogalacto-sucrose, Sansweet su 100, Trichlorogalactosucrose
Synthetic
Skin Conditioner
Clean
OriginDerived from sucrose through selective chlorination of hydroxyl groups to replace three hydroxyl molecules with chlorine atoms. Synthesized via multi-step chemical modification of sucrose using chlorinating agents under controlled laboratory conditions.
alpha-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy,
Solubility Freely soluble in water, methanol and ethanol; Slightly soluble in ethyl acetate
Formula
C12H19Cl3O8
Mol. Weight
397.60
CAS #
56038-13-2
Form
Powder
State
Dry Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 657)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 657)
Concentration Guide
Leave-on0.2–0.6%
Rinse-off0.012–1.2%
0%50%100%
CIR reported use · 2013 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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