Tetramethyl Acetyloctahydronaphthalenes

Tetramethyl Acetyloctahydronaphthalenes 1
AKA: OTNE, Iso E Super
Synthetic
Fragrance
Skin Conditioner
Not Clean
Mixture of isomers:1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one;1-(1,2,3,4,5,6,7,8-Octahydro-2,3,5,5-tetramethyl-2-naphthyl)ethan-1-one;1-(1,2,3,5,6,7,8,8a-Octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one (68155-67-9); 1-(1,2,3,4,6,7,8,8a-Octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one (68155-66-8)
CAS #
54464-57-2, 54464-59-4, 68155-66-8, 68155-67-9
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic polycyclic compound developed in the mid-20th century for use as a fragrance ingredient and solvent in cosmetics. It provides a woody, musky scent profile and was created to offer stability and longevity in fragrance formulations.
EWG
4
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
ewg-4
all-shades-safe
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
General
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: CosIng · EWG · CIR