murphyTetrapotassium Pyrophosphate
AKA: 7320-34-5, Potassium diphosphate, Diphosphoric acid, Tetrapotassium salt, Tetrapotassium diphosphorate, Pyrophosphoric acid
Synthetic
Chelating Agent
Clean
OriginSynthesized from potassium salts and phosphoric acid through chemical combination and neutralization reactions. Produced by controlled reaction of potassium hydroxide with pyrophosphoric acid, then crystallized and purified.
The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Tetrapotassium Pyrophosphate...
Solubility Soluble in water, insoluble in ethanol
Formula
K4O7P2
Mol. Weight
330.34
CAS #
7320-34-5
Form
Powder
State
Potassium tetrapyrophosphate is a whitish-colored powdered solid. It is toxic by ingestion, and/or inhalation. Contact with the substance should be avoided.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Buffering
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Oral Care
Stabilizes pH
Removes Metal Ions
Supports dental health
Maintains optimal pH
Binds metal ions
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Skin Irritation Results
6 studies / 3 irritating / 3 not irritating / reactions slight to mild (CIR 710)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild to moderate (CIR 710)
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2015 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR