Tetrasodium EDTA

AKA: Sodium edetate, Edetate sodium, EDTA tetrasodium, EDTA sodium, Calsol, EDTA tetrasodium salt, Versene 100, Endrate tetrasodium, Sequestrene
Synthetic
Chelating Agent
Clean
Tetrasodium ethylenediaminetetraacetate
Solubility Slightly soluble in ethanol
Formula
C10H12N2Na4O8
Mol. Weight
380.17
CAS #
64-02-8
Form
Powder
State
Dry Powder; Liquid; Other Solid; Dry Powder, Water or Solvent Wet Solid; NKRA; Pellets or Large Crystals; Dry Powder, Liquid
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Reduces Inflammation
Fights Bacteria
Wound Healing
Binds metal ions
Traditional Use
Synthetic chelating agent developed in the mid-20th century to bind metal ions and prevent oxidation in cosmetics. Created to improve product shelf-life and prevent discoloration.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR