murphyTetrasodium Etidronate
AKA: 3794-83-0, Tarpinel 4NL, Turpinal 4NL, Sequion 10Na4, Etidronate tetrasodium, Defloc EN 43, Dequest 2016
Synthetic
Emulsifier
Chelating Agent
Not Clean
OriginSynthesized from phosphonic acid derivatives and sodium compounds through chemical synthesis methods. Produced by reacting etidronic acid with sodium hydroxide to form the tetrasodium salt.
Tetrasodium (1-hydroxyethylidene)bisphosphonate
Formula
C2H4Na4O7P2
Mol. Weight
293.96
CAS #
3794-83-0
State
Liquid; Pellets or Large Crystals; Dry Powder, Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Emulsion Stabilising
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Viscosity Controlling
Removes Metal Ions
Stabilizes Emulsion
Controls Viscosity
Binds metal ions
Keeps product blended
Controls product thickness
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 729)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild to moderate (CIR 729)
Concentration Guide
Leave-on0.02–0.06%
Rinse-off0.009–0.15%
0%50%100%
CIR reported use · 2015 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR