Tetrasodium Glutamate Diacetate

Tetrasodium Glutamate Diacetate molecular structure
molecular structure · PubChem
AKA: 51981-21-6, Tetrasodium N, N-Bis(carboxymethyl)-L-glutamate, N-bis(carboxylatomethyl)-L-glutamate, DISSOLVINE GL, CHELEST CMG-40
Synthetic
Skin Conditioner
Amino Acid
Synthetic
Clean
Tetrasodium Glutamate Diacetate is a cosmetic ingredient. Also known as 51981-21-6. Rated low hazard by EWG.
Formula
C9H9NNa4O8
Mol. Weight
351.13
CAS #
51981-21-6
Form
Powder
State
Pellets or Large Crystals, Liquid; Dry Powder; Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Removes Metal Ions
Binds metal ions
EWG
2
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not an Irritant
all-shades-safe
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Skin Types
●all-skin-types
Best For
General
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Anti-Aging Hand Cream
COOLA
 →
The New Tendency Complete Set
Nécessaire
 →
beginner retinol gel 0.1%
Cocokind
 →
calm & clarify duo
Cocokind
 →
Everyday Radiance Essentials
Bloom Effects
 →
Golden Hour Body Butter
Ursa Major
 →
Golden Hour Body Serum
Ursa Major
 →
holi (sun) spf 50 dewy tinted skin drops
Agent Nateur
 →
The Hand Cream + The Tube Key
Nécessaire
 →
holi (soleil) firming & plumping mineral spf 50 sunscreen
Agent Nateur
 →
Hoppin’ Fresh Body Wash
Ursa Major
 →
Super Serum Skin Tint SPF 30
ILIA Beauty
 →
lactic acid cleanser duo
Agent Nateur
 →
The New Tendency Duo
Nécessaire
 →
peptide fine line eye gel
Cocokind
 →
Radiance Reset
Bloom Effects
 →
rise + shine trio
Cocokind
 →
ReFresh Eye Brightener Broad Spectrum SPF 30 + Correcting Tint
RMS Beauty
 →
SunCoverup Super Tint SPF 50
RMS Beauty
 →
Brightening Bubbling Cleanser
Alpyn Beauty
 →
Super Serum Skin Tint SPF 40
ILIA Beauty
 →
The ILIA Look
ILIA Beauty
 →
Daily SPF 50 Primer
Indie Lee
 →
ReFresh Eye Brightener SPF 30 + Correcting Tint
RMS Beauty
 →
SunCoverup Super Tint Broad Spectrum SPF 50 Sunscreen
RMS Beauty
 →
Supernatural Radiance Serum Broad Spectrum SPF 30 Sunscreen
RMS Beauty
 →
The Brighten Up Essentials
RMS Beauty
 →
SOS Rescue Spray - Standard Size
Tower 28 Beauty
 →
Golden Hour Body Butter
Ursa Major
 →
Golden Hour Body Serum
Ursa Major
 →
Forest Water Hyaluronic Serum
Ursa Major
 →
Sunlit Essentials Set
Indie Lee
 →
the after (glow) set: rose quartz
Agent Nateur
 →
the after (glow) set: ruby
Agent Nateur
 →
the body duo
Agent Nateur
 →
the vitamin c and hyaluronic brightening duo
Agent Nateur
 →
The Hand Duo
Nécessaire
 →
The Hand-Lip Moisture Duo
Nécessaire
 →
SOS Rescue Spray Party Pack
Tower 28 Beauty
 →
GoGo Cooling Shimmer Eyeshadow
Tower 28 Beauty
 →
Tulip Dew Sunscreen Serum
Bloom Effects
 →
youthful duo
Cocokind
 →
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR