Tocopheryl Phosphate

AKA: 425429-22-7, Beta-Alanine, Compd. with 3, 4-dihydro-2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6-yl dihydrogen phosphate (1:1), I(2)-Alanine, 12-trimethyltridecyl)-2H -1-benzopyran-6- yl dihydrogen phosphate (1:1)
Synthetic
Cleanser
Emulsifier
Skin Conditioner
Hair Care
Clean
OriginDerived from plant-based vitamin E sources, typically obtained from vegetable oils like soybean or sunflower oil. Synthesized through phosphorylation of tocopherol, attaching a phosphate group to the vitamin E molecule.
Tocopheryl Phosphate is a complex mixture of esters of Tocopheryl (q.v.) Phosphoric Acid (q.v.)
Formula
C47H86NO9P
Mol. Weight
840.20
CAS #
425429-22-7
Form
Powder
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Aging
Antioxidant
Strengthens Barrier
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Eye Irritant
1 study / 1 not irritating (CIR 667)
Not a Sensitizer
1 study / 1 not sensitizing (CIR 667)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions slight to moderate (CIR 667)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2018
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR