Tosylamide/Formaldehyde Resin

AKA: Tosylamide Formaldehyde Resin, Nail Polish Resin
Plant-Derived Synthetic
Occlusive
Not Clean
OriginSynthesized from p-toluenesulfonamide and formaldehyde, belonging to the sulfonamide-formaldehyde resin chemical family. Produced through condensation polymerization of tosylamide with formaldehyde under controlled conditions.
Benzenesulfonamide, 4-methyl-, polymer with formaldehyde
CAS #
25035-71-6
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Allergen Warning
⚠️ Formaldehyde
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Plasticiser
Anti-Inflammatory
Moisturizing
Fights Acne
Creates protective layer
Adds flexibility
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
Not a Sensitizer
6 studies / 6 not sensitizing / plus 4 case reports (CIR 177)
Not Phototoxic
Product formulation test found no phototoxicity in the CIR safety assessment (CIR 177)
Eye Irritant in Testing
4 studies / 4 irritating / reactions slight to severe (CIR 177)
Mixed Skin Irritation Results
13 studies / 5 irritating / 8 not irritating / reactions minimal to mild (CIR 177)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR