Tribehenin

AKA: 18641-57-1, Glyceryl tribehenate, Compritol 888, Tribehenoyl glycerol, Behenic acid, 1, 2, 3-propanetriol ester, 3-Propenetriol tridocosanoate, Dub bg, Compritol 888 cg
Fleuressence
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Synthetic
Skin Conditioner
Synthetic
Clean
OriginDerived from behenic acid, a long-chain fatty acid found in plant oils like rapeseed and peanut oil. Synthesized through esterification of behenic acid with glycerol or other polyols via catalytic reaction.
Tribehenin is a cosmetic ingredient. Also known as 18641-57-1. Rated low hazard by EWG.
Formula
C69H134O6
Mol. Weight
1059.80
CAS #
18641-57-1
State
Solid
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Softens & Smooths
Smooths and softens skin
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not Comedogenic
Product formulation test found no comedogenicity in the CIR safety assessment (CIR 316 and 742)
Not a Sensitizer
6 studies / 6 not sensitizing (CIR 742)
Mixed Eye Irritation Results
7 studies / 2 irritating / 5 not irritating / reactions mild to moderate (CIR 316 and 742)
Mixed Skin Irritation Results
6 studies / 1 irritating / 5 not irritating / reactions mild (CIR 316 and 742)
Concentration Guide
Leave-on0.002–15%
Rinse-off0.002–7%
0%50%100%
CIR reported use · 2017 survey
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR