Tricaprylin

AKA: Trioctanoin, 538-23-8, Tricaprilin, Glycerol trioctanoate, Rato, Glycerol tricaprylate, Trioctanoylglycerol, Glyceryl trioctanoate
Synthetic
Skin Conditioner
Synthetic
Clean
OriginDerived from caprylic acid (C8 fatty acid), a medium-chain fatty acid found in coconut oil and other plant sources. Synthesized through esterification of caprylic acid with glycerol under catalytic conditions.
Trioctanoin is a triglyceride obtained by acylation of the three hydroxy groups of glycerol by octanoic acid. Used as an alternative energy source to glucose for patients with mild to moderate Alzheimer's disease. It has a role as an anticonvulsant and a plant metabolite. It is a triglyceride and an octanoate ester.
Solubility less than 1 mg/mL at 72 °F (NTP, 1992)
Formula
C27H50O6
Mol. Weight
470.70
CAS #
538-23-8
Form
Liquid
State
Tricaprylin is an odorless viscous clear colorless to amber-brown liquid. (NTP, 1992)
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Perfuming
Softens and smooths skin
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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