Triethylene Glycol
molecular structure · PubChem
AKA: 112-27-6, Triglycol, 2'-(Ethane-1, 2-diylbis(oxy))diethanol, 2'-Ethylenedioxydiethanol, Trigen, 2-[2-(2-Hydroxyethoxy)ethoxy]ethanol, Triethylenglykol, Triethyleneglycol, 1, 2-Bis(2-hydroxyethoxy)ethane
Synthetic
Fragrance
Not Clean
Triethylene glycol is a poly(ethylene glycol) that is octane-1,8-diol in which the carbon atoms at positions 3 and 6 have been replaced by oxygen atoms. It has a role as a plasticiser. It is a primary alcohol, a diol and a poly(ethylene glycol).
Solubility greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Formula
C6H14O4
Mol. Weight
150.17
CAS #
112-27-6
Form
Powder
State
Triethylene glycol is a colorless liquid with a mild odor. Dense than water. (USCG, 1999)
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Viscosity Controlling
Antioxidant
Moisturizing
Provides scent
Controls product thickness
Traditional Use
Synthetic humectant developed in the 20th century as a modern cosmetic ingredient to attract and retain moisture in skincare products, replacing some traditional plant-based humectants.
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR