murphyTriethylene Glycol Dimethacrylate
AKA: 109-16-0, Tedma, NK ester 3G, Triethylene dimethacrylate, TEGDMA, TGM 3PC, TGM 3S, TGM 3, Triethyleneglycol dimethacrylate
Synthetic
Skin Conditioner
Not Clean
OriginDerived from ethylene glycol and methacrylic acid, both petrochemical-based compounds from fossil fuels. Synthesized through esterification reaction between triethylene glycol and methacrylic acid under catalytic conditions.
2,2'-ethylenedioxydiethyl dimethacrylate
Solubility > 10% in acetone
Formula
C14H22O6
Mol. Weight
286.32
CAS #
109-16-0
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Functions
Nail Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Antioxidant Protection
Strengthens nails
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 mixed / reactions mild (CIR 339)
Mixed Sensitization Results
3 studies / 2 sensitizing / 1 not sensitizing / plus 8 case reports (CIR 339)
Concentration Guide
Leave-on8.7–20%
Rinse-offNot reported
0%50%100%
CIR reported use · 2020 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR