Triisocetyl Citrate

AKA: 93385-14-9, Jeechem TISC, Citmol 316, Triisohexadecyl citrate, 1, 2, 3-Propanetricarboxylic acid, Triisohexadecyl ester, 3-triisohexadecyl ester
Synthetic
Emollient
Skin Conditioner
Clean
OriginDerived from citric acid and isocetyl alcohol, both synthetic or petroleum-derived compounds. Synthesized through esterification reaction between citric acid and isocetyl alcohol under catalytic conditions.
2-Hydroxy-1,2,3-propanetricarboxylic acid, triisohexadecyl ester
Formula
C54H104O7
Mol. Weight
865.40
CAS #
93385-14-9
Form
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.6–3%
Rinse-offNot reported
0%50%100%
CIR reported use · report published 2014
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR