Triisopropanolamine

Triisopropanolamine molecular structure
molecular structure · PubChem
AKA: 122-20-3, TIPA, TRIS(2-HYDROXYPROPYL)AMINE, Tri-2-propanolamine, Tri-iso-propanolamine, Tris(2-propanol)amine, Tris(2-hydroxy-1-propyl)amine, 2-Propanol
Synthetic
Not Clean
1,1',1''-Nitrilotripropan-2-ol
Solubility Soluble (NTP, 1992)
Formula
C9H21NO3
Mol. Weight
191.27
CAS #
122-20-3
Form
Liquid
State
Triisopropanolamine is a white solid with slight odor of ammonia. Denser than water.
Functions
Buffering
Stabilizes pH
Traditional Use
A synthetic chemical compound developed in the 20th century as a pH buffer and emulsifier in cosmetics. Used to neutralize acids and stabilize formulations.
EWG
7
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
🧂Conflict of interest.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR